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Flights from Santiago to Chicago
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Flights from Santiago to Chicago Starting at £179

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Round-trip
      • STI14:30
        10h 6m
        1 stop
        ORD22:36
        Fri, Feb 7|Santiago - Chicago|Delta Air Lines
        £179£321
        44% OFF
        44% OFF
        £321£179

        Choose Delta Air Lines flights from Santiago to Chicago. The one-way connecting flight with Delta Air Lines departs from Cibao International Airport on Fri, Feb 7, arriving at O'Hare International Airport. One-way Prices start from £179 including taxes and charges.

      • STI06:35
        11h 42m
        1 stop
        ORD16:17
        Sat, Feb 8|Santiago - Chicago|Delta Air Lines
        £179£321
        44% OFF
        44% OFF
        £321£179

        Choose Delta Air Lines flights from Santiago to Chicago. The one-way connecting flight with Delta Air Lines departs from Cibao International Airport on Sat, Feb 8, arriving at O'Hare International Airport. One-way Prices start from £179 including taxes and charges.

      • STI06:00
        17h 52m
        1 stop
        ORD21:52
        Tue, Dec 31|Santiago - Chicago|United Airlines
        £179£321
        44% OFF
        44% OFF
        £321£179

        Choose United Airlines flights from Santiago to Chicago. The one-way connecting flight with United Airlines departs from Cibao International Airport on Tue, Dec 31, arriving at O'Hare International Airport. One-way Prices start from £179 including taxes and charges.

      • STI12:49
        12h 11m
        1 stop
        ORD23:00
        Wed, Dec 25|Santiago - Chicago|United Airlines
        £180
        £180

        Choose United Airlines flights from Santiago to Chicago. The one-way connecting flight with United Airlines departs from Cibao International Airport on Wed, Dec 25, arriving at O'Hare International Airport. One-way Prices start from £180 including taxes and charges.

      • STI06:00
        12h 26m
        1 stop
        ORD16:26
        Thu, Jan 30|Santiago - Chicago|United Airlines
        £204
        £204

        Choose United Airlines flights from Santiago to Chicago. The one-way connecting flight with United Airlines departs from Cibao International Airport on Thu, Jan 30, arriving at O'Hare International Airport. One-way Prices start from £204 including taxes and charges.

      • STI12:49
        9h 36m
        1 stop
        ORD20:25
        Fri, Feb 7|Santiago - Chicago|United Airlines
        £216
        £216

        Choose United Airlines flights from Santiago to Chicago. The one-way connecting flight with United Airlines departs from Cibao International Airport on Fri, Feb 7, arriving at O'Hare International Airport. One-way Prices start from £216 including taxes and charges.

      • STI11:58
        22h 48m
        1 stop
        ORD08:46
        Fri, Feb 7|Santiago - Chicago|Jetblue Airways
        £216
        £216

        Choose Jetblue Airways flights from Santiago to Chicago. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Fri, Feb 7, arriving at O'Hare International Airport. One-way Prices start from £216 including taxes and charges.

      • STI06:45
        15h 28m
        1 stop
        ORD20:13
        Sat, Feb 8|Santiago - Chicago|Jetblue Airways
        £216
        £216

        Choose Jetblue Airways flights from Santiago to Chicago. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Sat, Feb 8, arriving at O'Hare International Airport. One-way Prices start from £216 including taxes and charges.

      • STI06:00
        12h 26m
        1 stop
        ORD16:26
        Mon, Feb 10|Santiago - Chicago|United Airlines
        £217
        £217

        Choose United Airlines flights from Santiago to Chicago. The one-way connecting flight with United Airlines departs from Cibao International Airport on Mon, Feb 10, arriving at O'Hare International Airport. One-way Prices start from £217 including taxes and charges.

      • STI04:50
        12h 54m
        1 stop
        ORD15:44
        Thu, Jan 30|Santiago - Chicago|Jetblue Airways
        £217
        £217

        Choose Jetblue Airways flights from Santiago to Chicago. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Thu, Jan 30, arriving at O'Hare International Airport. One-way Prices start from £217 including taxes and charges.

      • STI01:00 pm
        3h 5m
        Nonstop
        CHI02:00 pm
        Wed, Jan 1|Santiago - Chicago|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Find the best time to fly from Santiago to Chicago

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Airlines Flying from Santiago to Chicago

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Frontier Airlines
From £119
Delta Air Lines
From £179
United Airlines
From £180
American Airlines
From £199
Jetblue Airways
From £216

Find more flights and airlines

Alternative Routes from Santiago to Chicago

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Santiago to Chicago.

  • Cheapest
    Frontier Airlines
    STI
    19:43
    19h 37m
    2 transfer
    ORD
    13:20
    Cibao International Airport - O'Hare International Airport
    Mon, Feb 24Frontier Airlines
    £119
  • Frontier Airlines
    STI
    19:43
    45h 30m
    2 transfer
    MDW
    15:13
    Cibao International Airport - Midway International Airport
    Sun, Feb 23Frontier Airlines
    £122
  • Frontier Airlines
    STI
    19:43
    45h 30m
    2 transfer
    MDW
    15:13
    Cibao International Airport - Midway International Airport
    Sun, Feb 23Frontier Airlines
    £122
    Find More Flights

FAQ

  • When are flight tickets from Santiago (STI) to Chicago (CHI) the cheapest?

    Airlines adjust prices for flights from Santiago to Chicago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Santiago (STI) to Chicago (CHI) cost?

    According to Trip.com's data, the lowest price is around £322.

  • What is the transportation method from the main airport to downtown in Chicago?

    • The distance from O'Hare International Airport to downtown is about 25 km. It takes about 40 minutes by taxi.
    • The distance from Midway International Airport to downtown is about 14 km. It takes about 30 minutes by taxi.

How to find a cheap flight from Santiago to Chicago

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santiago to Chicago. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Santiago to Chicago

Cheapest nonstop flight price£179
Off-season for travelDecember
Peak season for travelSeptember
Flight distance2,970.22 km
Popular airlineJetblue Airways

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