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Buffalo Niagara International Airport to Des Moines International Airport flight

Search for flights from Buffalo to Des Moines and check out affordable one-way and round-trip options.

      • BUF 12:50
        5h 12m
        1 stop
        DSM 17:02
        Buffalo - Des Moines | Sat, May 2 | Delta Air Lines
        DSM 07:34
        5h 33m
        1 stop
        BUF 14:07
        Des Moines - Buffalo | Thu, May 7 | Delta Air Lines
        €282 €463
        39% off
        39% off
        €463 €282
      • BUF 17:55
        4h 32m
        1 stop
        DSM 21:27
        Buffalo - Des Moines | Wed, Apr 1 | United Airlines
        DSM 11:09
        5h 21m
        1 stop
        BUF 17:30
        Des Moines - Buffalo | Wed, Apr 8 | American Airlines
        €301 €463
        35% off
        35% off
        €463 €301
      • BUF 06:15
        4h 31m
        1 stop
        DSM 09:46
        Buffalo - Des Moines | Wed, Apr 8 | Delta Air Lines
        DSM 17:47
        4h 8m
        1 stop
        BUF 22:55
        Des Moines - Buffalo | Sun, Apr 12 | Delta Air Lines
        €304 €463
        34% off
        34% off
        €463 €304
      • BUF 13:00
        4h 54m
        1 stop
        DSM 16:54
        Buffalo - Des Moines | Thu, Mar 26 | Delta Air Lines
        DSM 06:15
        4h 29m
        1 stop
        BUF 11:44
        Des Moines - Buffalo | Sun, Mar 29 | Delta Air Lines
        €310
        33% off
        €463 €310
      • BUF 18:02
        6h 15m
        1 stop
        DSM 23:17
        Buffalo - Des Moines | Tue, Apr 7 | United Airlines
        DSM 13:10
        6h 33m
        1 stop
        BUF 20:43
        Des Moines - Buffalo | Tue, Apr 14 | United Airlines
        €327
        28% off
        €463 €327
      • BUF 17:50
        6h 4m
        1 stop
        DSM 22:54
        Buffalo - Des Moines | Sat, May 2 | United Airlines
        DSM 11:40
        4h 14m
        1 stop
        BUF 16:54
        Des Moines - Buffalo | Thu, May 7 | United Airlines
        €343
        26% off
        €463 €343
      • BUF 18:00
        6h 49m
        1 stop
        DSM 23:49
        Buffalo - Des Moines | Sat, May 2 | American Airlines
        DSM 06:00
        7h 21m
        1 stop
        BUF 14:21
        Des Moines - Buffalo | Thu, May 7 | American Airlines
        €346
        25% off
        €463 €346
      • BUF 11:31
        13h 18m
        1 stop
        DSM 23:49
        Buffalo - Des Moines | Sat, Apr 11 | American Airlines
        DSM 06:00
        7h 21m
        1 stop
        BUF 14:21
        Des Moines - Buffalo | Sun, Apr 12 | American Airlines
        €359
        22% off
        €463 €359
      • BUF 17:32
        5h 21m
        1 stop
        DSM 21:53
        Buffalo - Des Moines | Tue, Apr 7 | American Airlines
        DSM 06:00
        7h 21m
        1 stop
        BUF 14:21
        Des Moines - Buffalo | Tue, Apr 14 | American Airlines
        €370
        20% off
        €463 €370
      • BUF 14:59
        5h 28m
        1 stop
        DSM 19:27
        Buffalo - Des Moines | Sun, Apr 5 | Delta Air Lines
        DSM 17:47
        4h 8m
        1 stop
        BUF 22:55
        Des Moines - Buffalo | Sun, Apr 12 | Delta Air Lines
        €375
        19% off
        €463 €375
      • BUF 13:00
        17h 25m
        1 stop
        DSM Invalid Date
        Buffalo - Des Moines | Sun, Mar 22 | Normal Airline
        DSM 15:00
        6h
        Direct
        BUF 16:00
        Des Moines - Buffalo | Tue, Mar 24 | Normal Airline
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      • BUF 12:09
        6h 36m
        1 stop
        DSM 17:45
        Buffalo - Des Moines | Wed, May 6 | Delta Air Lines
        €137 €221
        38% off
        38% off
        €221 €137
      • BUF 06:00
        5h 48m
        1 stop
        DSM 10:48
        Buffalo - Des Moines | Wed, Apr 8 | Delta Air Lines
        €148 €221
        33% off
        33% off
        €221 €148
      • BUF 17:50
        6h 19m
        1 stop
        DSM 23:09
        Buffalo - Des Moines | Wed, May 6 | United Airlines
        €163 €221
        26% off
        26% off
        €221 €163
      • BUF 13:00
        4h 54m
        1 stop
        DSM 16:54
        Buffalo - Des Moines | Thu, Mar 26 | Delta Air Lines
        €168
        24% off
        €221 €168
      • BUF 06:00
        6h 5m
        1 stop
        DSM 11:05
        Buffalo - Des Moines | Sat, Apr 18 | Delta Air Lines
        €168
        24% off
        €221 €168
      • BUF 06:15
        4h 31m
        1 stop
        DSM 09:46
        Buffalo - Des Moines | Sun, Apr 12 | Delta Air Lines
        €168
        24% off
        €221 €168
      • BUF 15:01
        5h 32m
        1 stop
        DSM 19:33
        Buffalo - Des Moines | Wed, May 6 | American Airlines
        €169
        24% off
        €221 €169
      • BUF 07:00
        6h 29m
        1 stop
        DSM 12:29
        Buffalo - Des Moines | Sat, Apr 25 | United Airlines
        €169
        24% off
        €221 €169
      • BUF 06:05
        4h 49m
        1 stop
        DSM 09:54
        Buffalo - Des Moines | Thu, Apr 16 | Delta Air Lines
        €179
        19% off
        €221 €179
      • BUF 06:00
        6h 5m
        1 stop
        DSM 11:05
        Buffalo - Des Moines | Wed, Apr 15 | Delta Air Lines
        €179
        19% off
        €221 €179
      • BUF 13:00
        17h 25m
        1 stop
        DSM Invalid Date
        Buffalo - Des Moines | Sun, Mar 22 | Normal Airline
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Displayed flight fares from Buffalo to Des Moines are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Selected Airlines from Buffalo Niagara International Airport to Des Moines International Airport

See which airlines fly from Buffalo to Des Moines. Find the airline that best meets your travel needs by comparing prices and treat yourself to an enjoyable journey.

Delta Air Lines
From €137
United Airlines
From €163
American Airlines
From €169
Frontier Airlines
From €173
Jetblue Airways
From €345

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Flight Schedule from Buffalo Niagara International Airport to Des Moines International Airport

Check the schedule for flights from Buffalo to Des Moines and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL2898

    Buffalo Niagara International Airport

    06:25

    BUF

    1h 19m

    Direct

    07:44

    DTW

    S M T W T F S
    Search

  2. DL5058

    Detroit Metropolitan Wayne County Airport

    08:25

    DTW

    1h 59m

    Direct

    09:24

    DSM

    S M T W T F S

  3. DL3983

    Buffalo Niagara International Airport

    13:00

    BUF

    1h 16m

    Direct

    14:16

    DTW

    S M T W T F S
    Search

  4. DL5345

    Detroit Metropolitan Wayne County Airport

    15:55

    DTW

    1h 55m

    Direct

    16:50

    DSM

    S M T W T F S

  5. AA5243

    Buffalo Niagara International Airport

    05:30

    BUF

    1h 30m

    Direct

    07:00

    DCA

    S M T W T F S
    Search

  6. AA5432

    Ronald Reagan Washington National Airport

    19:56

    DCA

    2h 55m

    Direct

    21:51

    DSM

    S M T W T F S

  7. AA3956

    Buffalo Niagara International Airport

    17:29

    BUF

    1h 25m

    Direct

    18:54

    DCA

    S M T W T - S
    Search

  8. AA5432

    Ronald Reagan Washington National Airport

    19:56

    DCA

    2h 55m

    Direct

    21:51

    DSM

    S M T W T F S

  9. DL5362

    Buffalo Niagara International Airport

    15:45

    BUF

    1h 27m

    Direct

    17:12

    LGA

    S M T W T - S
    Search

  10. DL4904

    LaGuardia Airport

    17:45

    LGA

    3h 15m

    Direct

    20:00

    DSM

    S M T W T F S

  11. DL2664

    Buffalo Niagara International Airport

    06:00

    BUF

    2h 21m

    Direct

    08:21

    ATL

    S M T W T F S
    Search

  12. DL1704

    Hartsfield-Jackson Atlanta International Airport

    09:05

    ATL

    2h 13m

    Direct

    10:18

    DSM

    S M T W T F S
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Buffalo Niagara International Airport to Des Moines International Airport Flights Info

Flight distance1,237.63 km
Cheapest one-way ticket price€137
Cheapest return ticket price€282

FAQs for Buffalo Niagara International Airport to Des Moines International Airport Flights

  • How long is a flight from Buffalo Niagara International Airport to Des Moines International Airport?

    It takes around 4 hours 56 minutes to fly from Buffalo Niagara International Airport (buf) to Des Moines International Airport (dsm).
  • There are around 1 daily flights from Buffalo Niagara International Airport (BUF) to Des Moines International Airport (DSM).
  • Tickets cost around €403 in November, making it the cheapest month to book. Buffalo Niagara International Airport (BUF) to Des Moines International Airport (DSM) is a popular route, so don't forget to book your tickets in advance.
  • The route from Buffalo Niagara International Airport (BUF) to Des Moines International Airport (DSM) is quite popular. Without considering departure times or holidays, tickets cost around €403 in November, the most expensive month to book this route.
  • United Airlines is a very popular airline operating an average of 2 flights per month.